J. Thomas LaMont Quotes & Sayings

Among frail, elderly patients, C. diff can be fatal in approximately 5-10%. Some patients with severe C. diff end up losing their colon and have a permanent bag on their side to catch bodily waste, via a procedure known as an ileostomy. — J. Thomas LaMont

Once C. diff leaves the colon of the infected patient in a liquid stool, it usually converts to a spore that is like a seed that lies dormant in the hospital until it gets picked up by a suitable human host. Once swallowed, C. diff germinates (hatches) in the bowel and starts a new cycle of infection. — J. Thomas LaMont

Many people infected with C. diff are sick with diarrhea, abdominal pain, nausea, and weight loss. Others are "carriers" of C. diff with no signs or symptoms of disease. Some of these carriers have been recently infected with C. diff but have recovered and now feel well. But carriers still have the C. diff organism in their stools and can serve as a silent reservoir of infection in hospitals and nursing homes. — J. Thomas LaMont

Some studies have reported C. diff in food purchased in a supermarket. Dogs, horses, pigs, and rabbits can also be carriers of C. diff, although spread of disease from pets or domestic animals to humans has yet to be documented. Like most infections, it is usually impossible to pinpoint the source of C. diff. — J. Thomas LaMont

Testing stools for C. diff in patients after they have finished their Flagyl or Vanco for 10 days and after their bowel movements have returned to normal (that is, formed and not watery) is a waste of time and money, and is not helpful to the doctor or patient. — J. Thomas LaMont

Sometimes mothers of newborn babies have to take antibiotics for a urinary tract infection. The antibiotics can damage the protective stool barrier allowing C. diff to get in and cause infection. I — J. Thomas LaMont

The idea behind a stool transplant is to "reseed the lawn," so to speak. After exposure to weeks or months of antibiotics (including Vanco) the normal bowel flora - the organisms in your colon that help prevent infection - is weakened. They simply can't keep C. diff out. In other words, the normal barrier function of the colonic flora is gone, and C. diff gets right back in. So putting in some normal flora from a healthy donor is like reseeding the lawn - it restores the barrier. When that happens, C. diff cannot get back in, and the infection is cured. — J. Thomas LaMont

In the past five years, C. diff has spread across the globe, helped in large part by air travel, the availability and frequent use of antibiotics, and the graying of the world's population. — J. Thomas LaMont

C. diff can sometimes be life-threatening, even in healthy young adults. — J. Thomas LaMont

C. diff is not a simple "stomach bug" like viral gastroenteritis or food poisoning that disappears in nearly all patients after a week or two. — J. Thomas LaMont

have treated a few moms who probably caught C. diff from their newborns. I have also treated a neonatologist (a pediatric specialist in newborn diseases) who probably picked up C. diff at work from one of her sick newborns. — J. Thomas LaMont

Some older or very ill patients may not be suitable candidates for fecal transfer. Colonoscopy is an invasive procedure, especially for those patients who are too ill with other conditions like cancer, heart failure, dialysis, or Alzheimer's. — J. Thomas LaMont

Hospitals in almost every country have reported outbreaks of C. diff, and the number and severity of cases continues to soar. In 2010 there were 350,000 cases of C. diff diagnosed in U.S. hospitals. That means that of 1,000 patients admitted to U.S hospitals, 10 will become infected with C. diff, most of them elderly. In some hospitals and nursing homes, as many as one in five patients is infected. — J. Thomas LaMont