Simplemente Quotes & Sayings

In this model, there is a vicious cycle of events that results in the generation of a more and more repressed state. One of the predictions from this model is that repressive histone modifications attract DNA methyltransferases, which deposit DNA methylation near those histones. This methylation in turn attracts more repressive histone modifying enzymes, creating a self-perpetuating cycle that leads to an increasingly hostile region for gene expression. Experimental data suggest that in many cases this model seems to be right. Repressive histone modifications can act as the bait to attract DNA methylation to the promoter of a tumour suppressor gene. A key example of this is an epigenetic enzyme we met in the previous chapter, called EZH2. The EZH2 protein adds methyl groups to the lysine amino acid at position 27 on histone H3. This amino acid is known as H3K27. K is the single letter code for lysine (L is the code for a different amino acid called leucine). — Nessa Carey

Back then death was invisible for children like me, who went outside, running fearlessly along those fantastical streets, safe from history. The night of the earthquake was the first time I realized that everything could come tumbling down. Now I think it's a good thing to know. It's necessary to remember it every second. — Alejandro Zambra

These are amongst the last memories I shall relinquish to the page, though I am hanging onto them for now and for as long as I can. When they are gone, will there be anything left of me? Am I nothing but memory? — J.S. Watts

Found, to his surprise, that he had put an end to their threats. — V.S. Naipaul

Except for a human-powered hoist described — Steven Vogel

To every obstacle oppose patience, perseverance and soothing language. — Thomas Jefferson

If voting could change anything, it would be illegal. — Jello Biafra

And I proclaim that Shakespeare and Raphael are higher than the emancipation of the serfs, higher than nationality, higher than socialism, higher than the younger generation, higher than chemistry, higher than almost all mankind, for they are already the fruit, the real fruit of all mankind, and maybe the highest fruit there ever may be! A form of beauty already achieved, without the achievement of which I might not even consent to live ... — Fyodor Dostoyevsky

The American people have entered upon the mightiest civic struggle known to their history ... The Golden Rule is rejected by the heads of all the great departments of trade, and the law of Cain, which repudiates the obligations that we are mutually under to one another, is fostered and made the rule of action throughout the world. Corporate feudality has taken the place of chattel slavery and vaunts its power in every state. — James B. Weaver

I'm a generally optimistic person. — Alison Brie

A poem by Rudyard Kipling says derisively of people who despise soldiers and police that they make 'mock o' uniforms that guard you while you sleep.' You are likely to have a strong reaction pro or con to this sentiment and how Kipling expressed it, but you will not be able to defend your view with arguments that would convince someone who has the opposite reaction. If you are intellectually sophisticated you mare recognize that your conviction, however strong, cannot be shown to be 'right,' but at most reasonable. Yet that recognition will not weaken the strength of your conviction or its influence on your behavior." 105-06 (quoting Rudyard Kipling, Tommy.) — Richard A. Posner