Ezh2 Gene Quotes & Sayings

Because when you have been shown mercy by your Father in Heaven, you cannot keep it in inside. People who have been given mercy want to hand it out freely and generously. Once you have known the indescribable joy of receiving love when you had expected judgment, there is no containing the lengths you will go to give it away. And so the life inclined toward mercy becomes a beautiful offering to God. In your great need, you can turn your aching heart toward the Father and ask for His mercy. From the riches of His lavish love, He will tenderly give all that you need. Humbled by such a gracious gift, your heart will long to share with others who need mercy too. And when the one who gives mercy remains in the presence of God, all the mercy required is continually being provided. — Angela Thomas

In this model, there is a vicious cycle of events that results in the generation of a more and more repressed state. One of the predictions from this model is that repressive histone modifications attract DNA methyltransferases, which deposit DNA methylation near those histones. This methylation in turn attracts more repressive histone modifying enzymes, creating a self-perpetuating cycle that leads to an increasingly hostile region for gene expression. Experimental data suggest that in many cases this model seems to be right. Repressive histone modifications can act as the bait to attract DNA methylation to the promoter of a tumour suppressor gene. A key example of this is an epigenetic enzyme we met in the previous chapter, called EZH2. The EZH2 protein adds methyl groups to the lysine amino acid at position 27 on histone H3. This amino acid is known as H3K27. K is the single letter code for lysine (L is the code for a different amino acid called leucine). — Nessa Carey

Wake up and realize this is all made up of thoughts, just thoughts. Your appreciation of beauty is a thought; your aversion to an object that is ugly is a thought. Your craving or aversion is nothing but a passing thought in the mind. Realize this is just a thought and you will be free. — Sri Sri Ravi Shankar

I filled my sketchbook with drawings, very much as any educated girl of my generation might have kept a diary. — Gabriele Munter

One reason we desire explanations is that they separate us and make us feel safe. — Rabih Alameddine

There is increasing evidence that at least some of the targeting of epigenetic modifications can be explained by interactions with long ncRNAs. Jeannie Lee and her colleagues have recently investigated long ncRNAs that bind to a complex of proteins. The complex is called PRC2 and it generates repressive modifications on histones. PRC2 contains a number of proteins, and the one that interacts with the long ncRNAs is probably EZH2. The researchers found that the PRC2 complex bound to literally thousands of different long ncRNA molecules in embryonic stem cells from mice13. These long ncRNAs may act as bait. They can stay tethered to the specific region of the genome where they are produced, and then attract repressive enzymes to shut off gene expression. This happens because the repressive enzyme complexes contain proteins like EZH2 that are capable of binding to RNA. — Nessa Carey

Wine is like the incarnation
it is both divine and human — Paul Tillich

I always had that sense of being censored for the things that I thought. Why is it wrong to embroider your pants, or paint with acrylics on your clothing? Why is that weird? Isn't it weirder to want to be like everyone else? — Alice Sebold

When I'm in New York, I just want to walk down the street and feel this thing, like I'm in a movie. — Ryan Adams

Until the moment she actually sinks, the Titanic is unsinkable. — Julia Hughes

The space itself - its piles of papers representing decades of tangled history - reminded me of all that I didn't know and couldn't know. This itself is part of the wisdom of archives. By creating a finite space, where some things are included, some omitted, an archive challenges you to examine its dusty spaces, but more importantly, to search for what has been entirely left out. — Avi Steinberg

But I'm confident that my work - and the work of my staff - with our many young players over the last two years will begin to pay off for Mr. Taylor and Timberwolves fans. Now, as important new players are added to the mix, the future of this franchise should be a bright one, and I am thankful for the chance I had, to play a part in shaping that future. — Kurt Rambis

Irene Diamond's Fertile Ground is a provocative book. It stirs me to vigorous assent. It also triggers wide-eyed disbelief ... As it prods me to explosions of disagreement, it also provokes useful thought. — Janet Lembke

She [Chien-Shiung Wu] is a slave driver. She is the image of the militant woman so well known in Chinese literature as either empress or mother. — Emilio G. Segre

[Once Ummon asked a lesser light Are you a gardener> Yes it replied Why have turnips no roots> Ummon asked the gardener who could not reply Because said Ummon rainwater is plentiful] I think about this for a moment. Ummon's koan is not difficult now that I am regaining the knack of listening for the shadow of substance beneath the words. The little Zen parable is Ummon's way of saying, with some sarcasm, that the answer lies within science and within the antilogic which scientific answers so often provide. The rainwater comment answers everything and nothing, as so much of science has for so long. As Ummon and the other Masters teach, it explains why the giraffe evolved a long neck but never why the other animals did not. It explains why humankind evolved to intelligence, but not why the tree near the front gate refused to. — Dan Simmons

There is a core difference between sharing the gospel with the lost and imposing a specific moral standard on the unconverted. — Rosaria Champagne Butterfield