Ezh2 Enzyme Quotes & Sayings

Raising the debt limit on some levels is a ministerial act. It doesn't involve any new spending. — Jacob Lew

In this model, there is a vicious cycle of events that results in the generation of a more and more repressed state. One of the predictions from this model is that repressive histone modifications attract DNA methyltransferases, which deposit DNA methylation near those histones. This methylation in turn attracts more repressive histone modifying enzymes, creating a self-perpetuating cycle that leads to an increasingly hostile region for gene expression. Experimental data suggest that in many cases this model seems to be right. Repressive histone modifications can act as the bait to attract DNA methylation to the promoter of a tumour suppressor gene. A key example of this is an epigenetic enzyme we met in the previous chapter, called EZH2. The EZH2 protein adds methyl groups to the lysine amino acid at position 27 on histone H3. This amino acid is known as H3K27. K is the single letter code for lysine (L is the code for a different amino acid called leucine). — Nessa Carey

Many hands were willing to perform the last tender ministrations. It is characteristic of the small town and rural districts. Sympathy there takes concrete form. It becomes cakes and cinnamon rolls and sitting up nights, husking corn and washing dishes and closing the eyes of the neighboring dead. — Bess Streeter Aldrich

They're Lares. House gods."
"House gods," Percy said. "Like ... smaller than real gods, but larger than apartment gods? — Rick Riordan

Most of the more celebrated names among African-American authors, poets, and artists are known to the world because of their association with specific cultural arts movements. — Aberjhani

[Loco De Amor is] a euphoric, melodic romp across the hemisphere ... A joyful, fun musician's record from a really good guitarist — Jon Pareles

Every people has a right to choose the sovereignty under which they shall live. — Woodrow Wilson

When you pay attention to man, God also reciprocates with His attention — Sunday Adelaja

...he does not stir. She bows her head, looks at him, hugs him to her belly and weeps. No-one could imagine the depths of her misery. — Pierre Lemaitre

The greatest hunter is one who knows how to wait. — Erin Hunter

There is increasing evidence that at least some of the targeting of epigenetic modifications can be explained by interactions with long ncRNAs. Jeannie Lee and her colleagues have recently investigated long ncRNAs that bind to a complex of proteins. The complex is called PRC2 and it generates repressive modifications on histones. PRC2 contains a number of proteins, and the one that interacts with the long ncRNAs is probably EZH2. The researchers found that the PRC2 complex bound to literally thousands of different long ncRNA molecules in embryonic stem cells from mice13. These long ncRNAs may act as bait. They can stay tethered to the specific region of the genome where they are produced, and then attract repressive enzymes to shut off gene expression. This happens because the repressive enzyme complexes contain proteins like EZH2 that are capable of binding to RNA. — Nessa Carey

Pets reflect you like mirrors. When you are happy, you can see your dog smiling and when you are sad, your cat cries. — Munia Khan

In the backseat Moose and Squirrel inhabited a pair of six-year-old-twins, and wouldn't stop bickering and picking their noses. They were clearly in their element. — Neal Shusterman

It is much safer to be subject than it is to command. Many live in obedience more from necessity than from love. Such become discontented and dejected on the slightest pretext; they will never gain peace of mind unless they subject themselves wholeheartedly for the love of God. — Thomas A Kempis

I think in music and a lot of creative fields, people's egos get in the way of their ability of seeing the big picture. — John Oates

Professional success has not cured Prince's interpersonal problems, it's just given him the space to not have to say sorry. — Toure