Dopamine Receptors Quotes & Sayings

The money buys the drugs, the drugs work harder and harder to trick your blackened dopamine receptors into giving a damn about living. At some point you make a choice: fight your need the rest of your goddamned long-suffering life, or fill your need until it disappears into the grave with you. — Jeremy Robert Johnson

I never dreamt I could be an author when I grew up. It just didn't occur to me, because I thought you had to be a) academic, so go to university, things like that, and I didn't think I was clever, or b) dead because I just assumed all the authors in the library were dead. — Geraldine McCaughrean

I am entirely persuaded that the American public is more reasonable, restrained and mature than most of the broadcast industry's planners believe. Their fear of controversy is not warranted by the evidence. — Edward R. Murrow

The law, I said, which is the sequel of this and of all that has preceded, is to the following effect, - 'that the wives of our guardians are to be common, and their children are to be common, and no parent is to know his own child, nor any child his parent.' Yes, he said, that is a much greater wave than the other; and the possibility as well as the utility of such a law are far more questionable. I do not think, I said, that there can be any dispute about the very great utility of having wives and children in common; the possibility is quite another matter, and will be very much disputed. I — Plato

Just about anybody is a big girl in a small world but you gotta believe it on the inside, that you can be bigger than the rest of it. — Lizzo

Evolution has no foresight. Complex machinery develops its own agendas. Brains - cheat. Feedback loops evolve to promote stable heartbeats and then stumble upon the temptation of rhythm and music. The rush evoked by fractal imagery, the algorithms used for habitat selection, metastasize into art. Thrills that once had to be earned in increments of fitness can now be had from pointless introspection. Aesthetics rise unbidden from a trillion dopamine receptors, and the system moves beyond modeling the organism. It begins to model the very process of modeling. It consumes evermore computational resources, bogs itself down with endless recursion and irrelevant simulations. Like the parasitic DNA that accretes in every natural genome, it persists and proliferates and produces nothing but itself. Metaprocesses bloom like cancer, and awaken, and call themselves I. — Peter Watts

You start doing the addictive behavior to feel good and then your receptors get overloaded with dopamine, then you stop doing the addictive thing and some of the receptors have shut down and you don't have enough dopamine to feel good. So then you feel bad and go back to the addictive behavior to get more dopamine. The strange thing is that it works with what we think of as uppers and downers and whatever you call gambling - sidewaysers. — Bill Nye

Everybody got into the rugged outdoors business and into lifestyle merchandising and so forth and so on. And everybody was getting into catalogs and e-commerce and - you name it. It was just intense. — Leon Gorman

Got a wife and kid in Baltimore Jack, I went out for a ride and I never went back. Like a river that don't know where it's flowing, I took a wrong turn and I just kept going. — Bruce Springsteen

I know more now than I did in the past about the process of democratization. I know more about the pitfalls. — Meles Zenawi

Many studies link addiction to the orbitofrontal cortex (OFC), a cortical segment found near the eye socket, or orbit.5 In drug addicts, whether they are intoxicated or not, it doesn't function normally. The OFC's relationship with addiction arises from its special role in human behavior and from its abundant supply of opioid and dopamine receptors. It is powerfully affected by drugs and powerfully reinforces the drug habit. It also plays an essential supporting role in nondrug addictions. Of course, it doesn't function (or malfunction) on its own but forms part of an extensive and incredibly complex, multifaceted network - nor is it the only cortical area implicated in addiction. — Gabor Mate

A person's life isn't orderly ... it runs about all over the place, in and out through time. The present's hardly there; the future doesn't exist. Only love matters in the bits and pieces of a person's life. — William Trevor

The New World Order that is in the making must focus on the creation of a world of democracy, peace and prosperity for all. — Nelson Mandela

When I'm lying in my bed I think about life and I think about death and neither one particularly appeals to me. — Morrissey

In this case, Jane and Maura don't always agree on how to go about solving something. They both are very different in their approach and, a lot of times, that can lead to potential conflict, and then a debate in figuring out who and what is the right way to do it. — Sasha Alexander

In success, knowledge - In failure, lessons. — Garry Fitchett

No man can concentrate his attention upon evil, or even upon the idea of evil, and remain unaffected. To be more against the devil than for God is exceedingly dangerous. — Aldous Huxley

All authority has been given to Me in heaven and on earth. 19aGo therefore and make disciples of all the nations, baptizing them in the name of the Father and the Son and the Holy Spirit, 20teaching them to observe all that I commanded you; and lo, I am with you balways, even to the end of the age. [19 — Anonymous

Why does chronic self-administration of cocaine reduce the density of dopamine receptors? It's a simple matter of brain economics. The brain is accustomed to a certain level of dopamine activity. If it is flooded with artificially high dopamine levels, it seeks to restore the equilibrium by reducing the number of receptors where the dopamine can act. This mechanism helps to explain the phenomenon of tolerance, by which the user has to inject, ingest, or inhale higher and higher doses of a substance to get the same effect as before. — Gabor Mate